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In recent years, research on ferroptosis in the field of ophthalmology has gradually emerged, and a large amount of evidence has shown that it is closely related to the occurrence and development of ophthalmic diseases such as age-related macular degeneration (AMD), diabetic retinopathy (DR), retinal ischemiareperfusion injury (RIRI), retinitis pigmentosa, dry eye disease, cataracts, and glaucoma

The gene spans the length of 8552 nucleotides with 10 exons

3.5 Endothelial cell pyrotosis and BBB destruction after ICH Most studies on pyroptosis after ICH have focused on neuronal and glial cell death