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The depletion of cholesterol in local nociceptors due to organizational inflammation results in the loss and increased activity of lipid rafts around the sodium channel Na V 1.9, causing excessive excitation of peripheral nociceptive nerve endings and hyperalgesia

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El objetivo del presente trabajo es realizar una revisin de las causas de las alteraciones intestinales y de la microbiota intestinal en el paciente con ERC, analizando las consecuencias de dichos cambios y las intervenciones no farmacolgicas estudiadas hasta la actualidad

We found that OLA significantly decreased several L-carnitine metabolites levels in FES patients, including 2-octenoylcarnitine, 11z-octadecenylcarnitine, 9-decenoylcarnitine and L-palmitoylcarnitine