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Guideline Statements DIAGNOSIS Guideline Statement 1 The basic assessment should include a careful history, physical examination, and laboratory examination to document symptoms and signs that characterize IC/BPS and exclude other disorders that could be the cause of the patient's symptoms

The current biomarkers related to ferroptosis used in preclinical studies are nonspecific, such as GPX4 and ferritin[21, 33], which exist in other cell death modes and certain pathological conditions

Pluskal, T., Ueno, M

The therapeutic promise of AST lies not only in its molecular potency but also in its potential integration into multi-target interventions for complex neurodegenerative disorders