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Description

In addition to ALK5 , we identified that the knockdown of SMAD2 , a downstream target of ALK5, also protected against aSyn-induced toxicity

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10.1371/journal.pone.0055934 PLoS One 187 YunJ

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The function of an exosome is to cross barriers and carry proteins through barriers too large for cells to cross

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Although these epigenetic imprints cannot be detected in the genotype, since the DNA sequence is not changed, they can still very well be observed in the phenotype and can also be passed on to daughter cells [3]

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