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SARS-CoV-2 infection systemically activates metabolic pathways to enhance cellular viral replication capacity In the first step, we used scRNA-Seq data of samples from COVID-19 patients as input to our modeling workflow to predict viral replication capacity depending on cell type and disease severity 22

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A concentration of 50 mol/L artesunate selectively induces cell death in head and neck cancer cells without affecting normal cells by activating an iron-dependent, ROS-accumulating ferroptosis pathway [139]