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Common side effects: Talk to your doctor if any of these side effects bother you or do not go away after a few days: A slight dead arm for a couple of hours after the injection May feel slightly groggy the next morning but this will subside quickly pain, swelling or itchy skin where your injection was given feeling or being sick (nausea or vomiting) diarrhoea headaches feeling dizzy hot flushes In rare cases a rash can develop Serious side effects: Serious side effects are very rare but tell your doctor immediately if you get any of these symptoms after having treatment: irregular heartbeats or heartbeats that suddenly become more noticeable (palpitations) In rare cases, hydroxocobalamin can cause a serious allergic reaction (anaphylaxis)