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Moreover, Th17 differentiation drives the progression from NASH to HCC, rendering the inhibition of this differentiation a crucial intervention strategy for NASH (Huang Y

In digestive gastric ulcers, MEL promotes angiogenesis (222, 223), which accelerates healing, while in tissue hypoxia, such as age-related or in cancer, it inhibits neovascularization through inhibitory effects on HIF-1, HIF-1, VEGF and sphingosine kinase 1 (SPHK1) (224-227)