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The study by Neelakantan et al

As the deficiency is managed, the frequency can be reduced to weekly and then monthly for upkeep

Even reduced sun exposure during the cold winter months can affect your skins ability to synthesize vitamin D internally, a deficiency that can exacerbate bone loss and deteriorating skin quality

Subsequent development as an obesity drug was discontinued due to the small effect size, though research continues on its potential role in cartilage repair and localized metabolic applications