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Besides the neuroprotective effect, NF-B also has nerve injury effect

Gesundheitswesen 57, 214222

On the other hand, tryptophan can be metabolized via the indoleamine 2,3-dioxygenase (IDO) [58, 176] or through the enzyme tryptophan-2,3-dioxygenase (TDO) to form N-formylkynurenine (Kyn) [216]