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We propose a model describing the diverse roles of plant GSTs in the interactions of plant hosts with pathogenic microbes considering four different plant-pathogen interaction types (Table 1): (1) symptomless resistance (including basal resistance to bacteria and symptomless R gene-mediated resistance to viruses), (2) HR-associated resistance, (3) limiting susceptibility to systemic spread of pathogens and plant cell/tissue death (during infections by hemibiotrophic/necrotrophic fungi, bacteria, and viruses), (4) promoting susceptibility to biotrophic fungi and viruses (maintaining reduced conditions in infected non-necrotic plant tissues)

Lanthionine GSG in turn, forms an irreversible mixed disulfide with protein thiols that could lead to dysregulation of proteins that are normally regulated by reversible glutathionylation 81

Design of nanozyme-based wound dressings The treatment approach that relies solely on enzyme-like activity is limited, as it fails to comprehensively address the multifaceted challenges of oxidative stress, infection, and chronic inflammation present in traumatic wounds