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however, no clinical trials have been conducted with N-acetylcysteine, which constitutes a thiol compound and acts as a donor of L-cysteine, leading to replacement and increased levels of intracellular glutathione.2,46 The objective of this study was to evaluate the effectiveness of using oral N-acetylcysteine for eight weeks in the treatment of facial melasma in adult women

Subcellular localization experiments showed that coumarin 6-labeled CeO 2 MnO 2 (green fluorescence) could effectively enter HeLa cells after 4 h and that lysosomes were the main organelle targets of CeO 2 MnO 2 (Fig