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Another recent study found that LIFR (leukemia inhibitory factor receptor) sensitized HCC cell lines to sorafenib-induced ferroptosis both in vitro and in vivo, whereas loss of LIFR expression confers resistance to sorafenib-induced ferroptosis [99]

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Prooxidant behavior manifested by p53-mediated ROS formation can trigger cell death via apoptosis or ferroptosis (Jiang et al

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