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Because muscle has lymph and blood constantly in motion, the lollipop continually has blood and lymph washing over it and the lollipop will dissolve much more quickly, similar to what would happen if it were in a bowl of water that was gently being rocked back and forth

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PLoS Biol 20:e3001906 Borah K, Mendum TA, Hawkins ND, Ward JL, Beale MH, Larrouy-Maumus G, Bhatt A, Moulin M, Haertlein M, Strohmeier G et al (2021) Metabolic fluxes for nutritional flexibility of Mycobacterium tuberculosis

PubMed Hsieh, M.J., Liu, H.T., Wang, C.N., Huang, H.Y., Lin, Y., Ko, Y.S., Wang, J.S., Chang, V.H., & Pang, J.H