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Although the mechanism is not clear, research in animals suggests that riboflavin deficiency may impair iron absorption, increase intestinal loss of iron, and/or impair iron utilization for the synthesis of hemoglobin (16)

165 Both -HB and acetoacetate bypass glycolysis to reduce acetyl-CoA, which can then be channeled into the Krebs cycle, and can thus increase energy availability in the brain

After staying for a number of days at the decreased altitude (higher pressure), typically on the third day (Sunday afternoons), the family observed behavioral and symptomatic improvement

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