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Repetitive mTBI can produce more severe, longer-lasting cognitive impairments and neuropathology than a single injury and can result in outcomes similar to severe injury 10-13

joint involvement with pain/swelling/erythema), in the context of the patients history, with supporting evidence of elevated serum urate levels at a time other than during an acute attack Elevated serum urate levels alone are not diagnostic of gout, but may inform lifestyle changes (if relevant) and subsequent follow-up testing Treat gout flares with a NSAID, prednisone or low-dose colchicine