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Therefore, although the concept of FMT is highly attractive, its large-scale clinical application still needs to resolve key issues such as donor screening, preparation standardization, elucidation of mechanisms, and long-term safety assessment (Table 2)

When combined with SSRIs [selective serotonin reuptake inhibitors] and MAO [monoamine oxidase] inhibitors, it may lead to elevated blood pressure and could induce what is known as serotonin syndrome, said Wolf

In a randomized clinical trial, tesamorelin reduced visceral adipose tissue and liver fat in HIV-infected patients (Stanley et al., JAMA, 2014), and its Phase 3 program (Falutz et al.) established the visceral-fat effect that underpins its FDA approval