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Dietary Antigens are Available for Intestinal Transport Although the majority of dietary proteins are totally degraded by digestive enzymes and are absorbed in the form of nutrients (amino acids or dipeptides/tripeptides), some however can resist both the low pH of the gastric fluid and proteolytic enzyme hydrolysis, 5 meaning that large immunogenic peptides or intact proteins are capable of reaching the small intestinal lumen

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Hence, the infiltration of both macrophages and neutrophils should be increased in the DSS-induced EpCAM +/ mice compared to the WT + DSS group