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Interestingly, the highest dose tested (3.0 mcg/kg) produced a reduced response compared to 1.0 mcg/kg, suggesting a ceiling effect

His laboratory at the University of Zagreb has published the majority of preclinical studies examining BPC-157s effects across multiple organ systems and injury models, establishing it as one of the most comprehensively studied cytoprotective peptides in preclinical research

We need to understand how they show up and how to fight their effects

Impaired synaptic plasticity and decreased excitability of hippocampal glutamatergic neurons mediated by BDNF downregulation contribute to cognitive dysfunction in mice induced by repeated neonatal exposure to ketamine