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GIP has been shown to decrease food intake while blunting the metabolic adaptive responses that usually occur with calorie restriction resulting in weight reductions, and when combined with GLP-1 receptor agonism, may result in greater effects on markers of metabolic dysregulation such as body weight, glucose and lipids

The ACN was removed by vacuum centrifugation at 60 C and the final concentration was estimated by measuring absorbance at 280 nm on a NanoDrop 2000C (Thermo Scientific)

However, as many people look for ways to increase their levels, the question often shifts from why we need it to how we should take it

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