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Furthermore, it has been observed that fumarate and succinate share a similar affinity for the succinate-binding site of succinate dehydrogenase (SDH)

doi: 10.1038/oby.2011.256

80,114 Unmet Needs Malignancy Screening Although DM diagnosis typically triggers an extensive screening work-up to search for an underlying malignancy, a mortality benefit, which is the gold standard for supporting screening procedures, has never been demonstrated