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Removal of two hydrogens (H + + e ) from each thiol (by an oxidizing agent, not included in the figure, which represents an oxidation half-reaction), and concomitant formation of a new covalent bond - the disulfide bond - between the two sulfur atoms yields the lower structure at right

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Also, from the prospective cohort of pwRMS that entered the study, only 4566% of patients participated actively in completing the scales

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