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Indigenous Cattle (A2 Cattle) Conservation and Development- A Crucial Socioeconomic Component: A Review, Asian Journal of Dairy and Food Research, Agricultural Research Communication Center, No

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If ALD isnt well controlled, it may evolve into liver fibrosis, cirrhosis, eventually HCC with fatal property and poor prognosis

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Several factors have been identified related to the pathogenesis of ALS: OS, mitochondrial dysfunction, neuroinflammation, excitotoxicity due to an increase in the neurotransmitter glutamate, defect in axonal transmission and in the metabolism of RNA, apoptosis, cytoskeletal abnormalities, disruption of membrane trafficking, endoplasmic reticulum stress, protein misfolding and aggregation (Papadimitriou et al., 2010

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