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In orthomolecular medicine, quite dramatic healing effects have been reported as a result of B12 treatments on various forms of nitrosative stress (1)

In research models, DSIP has shown interactions with multiple neurochemical systems, including those involved in GABAergic signaling, stress response, and hormonal regulation

For fluorescence staining, we incubated samples for 2 h with Alexa-488 and Alexa-594 conjugated donkey antibodies (1:200) against mouse and rabbit immunoglobulins (Supplementary Figs 6 and 7 are representative images from two sets of immunolabelled cultures of NPCs and neurons)