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This biochemical profile correlates strongly with worse clinical progression, higher inflammatory markers, and the onset of severe neurological sequelae

de Graaf RA, Patel AB, Rothman DL, Behar KL

The role of these various enzyme activities in the liver is to convert fat-soluble toxins to water-soluble substances

(4) Inhibition of the electron transport chain: -syn aggregation impedes ATP production and increases the generation of ROS by diminishing the activity of mitochondrial complex I (Indrieri et al., 2020