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Iron overload induces the separation of IRP1 from IRE-like sequence, activating NOX4 transcription, increasing lipid peroxidation accumulation, and leading to significant dysregulation of mitochondrial morphology and function of osteoblasts

a set of mental skills that help people manage everyday tasks and solve problems requiring planning, flexibility in thinking and self-control (assessed by the Tower of London task) (F = 4.504, p = 0.015)