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Eur J Endocrinol 136:4551 Mauras N, O'Brien KO, Welch S, Rini A, Helgeson K, Vieira NE, Yergey AL (2000) Insulin-like growth factor I and growth hormone (GH) treatment in GH-deficient humans: differential effects on protein, glucose, lipid, and calcium metabolism

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Doses in preclinical studies have typically ranged from 10 nanograms to 10 micrograms per kilogram of body weight, administered daily