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23 for 200 students in grades 6-8 from the Panhandle region

As immune cells age, particularly T cells, mitochondrial efficiency declines, leading to reduced ATP production, increased ROS generation, and impaired mitophagy

Iron overload can induce profound mitochondrial dysfunction, characterized by impaired mitochondrial respiration, elevated mtROS production, mitochondrial membrane depolarization, and mitochondrial swelling [84, 85]