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A deeper understanding of the mechanisms of action of small molecules, the exact sites of action, the necessary dose to achieve the desired effect, and the optimal time to start antioxidant therapy for preventive or curative effects may provide a rational approach that may result in greater pharmacological and clinical success in low-molecular-weight antioxidant therapy

It should include the AEDG sequence, terminal groups, salt form, intact mass, tandem-MS evidence, peptide assay, impurity profile, acetate, water content, aggregation and batch information

Di WC, Lv JJ, Jiang S, Lu CX, Yang Z, Ma ZQ, et al

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