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2.2 Exclusion criteria 1) Studies related to simple hypoxia

Furthermore, they can be further modified using polyethylene glycol (PEG) in order to boost their stability

Moreover, increased lipid storage by tumor protein D52 (TPD52) represses lipid peroxidation and ferroptosis, whereas degradation of lipid droplets by autophagy (known as lipophagy) enhances free fatty acids production, and increases lipid peroxidation and ferroptosis [60]

These mechanisms include TLR, nod-like receptors, and C-lectin receptors, which have a high affinity for facilitating the downstream signaling cascade to initiate immune responses [186]