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This can be achieved by varying the amplitude and phase of the RF pulses at each transmit elementan approach known as static pTx, RF shimming, or B 1 + shimming (Mao et al., 2006), or by further varying the pulse shape transmitted by each element, known as dynamic pTx (Grissom et al., 2006

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As more than half of all COPD patients in the community have moderate COPD, a post-hoc analysis of the RESTORE study was performed to investigate whether the subgroup of COPD patients with moderate airflow limitation (57% of the total study population) would benefit specifically from erdosteine treatment [101]