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In patients with impaired renal function who will receive multiple doses of fluconazole tablets, an initial loading dose of 50 mg to 400 mg should be given

273 Using the lipid overload oxidative stress-related calcification model, it was found that the downregulation of p53 expression suppressed GPX4 and SLC7A11 expression and decreased the GSH/GSSG ratio, thereby promoting lipid peroxidation and ferroptosis