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Investigations are guided by clinical suspicion rather than routine panels: for example, thyroid function tests and ferritin may be checked if symptoms suggest deficiency or thyroid disease, while an androgen profile may be appropriate in women presenting with menstrual irregularity, hirsutism, or acne

Furthermore, silencing gankyrin in TNBC cells disrupted the formation of the gankyrin/MDM2 complex, hindered the degradation of p53, increased SLC7A11 expression, impeded cysteine uptake, and decreased GPX4 production

Dihydroartemisinin is the main antimalarial drug that improves pharmacokinetic properties based on artemisinin

Stephanie C, Fiona C, Eric I B, Charles N B, J Antonio A-Z, Alain B et al