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FIGURE 2 ROS-Dependent Mechanism of Iron Neurotoxicity Iron accumulation in the NS is a common feature in neurodegenerative diseases, including Alzheimers disease (Connor et al., 1992), Parkinsons disease (Gorell et al., 1995), Huntingtons disease (Dumas et al., 2012) or amyotrophic lateral sclerosis (Kwan et al., 2012)

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One approach to anti-aging medicine is to restore declining levels of endocrine hormones to more normal youthful levels, including thyroid, growth hormone, or sex hormones