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Although the quality of identified studies varied considerably, all relevant, published investigations were included in this overview so that the totality and diversity of information can be described, and issues for future research can be identified

Moderate-to-strong in vivo evidence: effects demonstrated in at least one well-controlled animal model, supported by quantitative microbial endpoints and/or relevant host-response measures, with greater weight given to replicated findings

Biomonitoring of the genotoxic and hepatotoxic effects and oxidative stress potentials of itraconazole in pregnant rats

Keating and colleagues created about 40 variants of their Mcl-1-blocking peptides, with staples in different positions