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Neuronal differentiation of the modified iPSC lines and the biosensor expression in iPSC-derived motor neurons We utilized a previously described protocol of highly efficient MN differentiation 38

m e represents the total mass of DOX loaded onto nanoparticles, and m t represents the total mass of DOX input

Cognitive deterioration and Alzheimer's disease Mitochondrial dysfunction and oxidative stress are thought to contribute to the onset and/or progression of several neurodegenerative diseases, especially Alzheimer's disease (AD) (102)