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Pathway analysis and gene set enrichment analysis on differentially expressed genes were performed using metascape web tool (metascape.org) 48 and GSEA ( 49 , and selected annotated gene lists from a gene ontology database ( were matched with differentially expressed genes

film, 0.25 m) and 5-m DuraGuard capillary in front of the analytical column (Agilent J&W GC Column) were used for the separation of metabolites

They do not suppress endocrine function and are generally well tolerated

This oxidation leads to endosomal dysfunction, highlighting how excessive oxidative stress can compromise cellular structures and activate specific cell death pathways