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E6 has been shown to decrease levels of the main intracellular antioxidants glutathione (GSH) and catalase (CAT), along with their enzymatic activities, resulting in increased ROS production and DNA damage [226]

Cells can access vital glutathione in one of three ways: De novo synthesis (the manufacture of fresh glutathione from scratch using two enzymes: glutathione synthetase, and glutamate cysteine ligase) Glutathione de novo synthesis Regeneration, via the enzyme glutathione reductase, of oxidized GSSG to reduced GSH By recycling cysteine from conjugated glutathione Some natural methods can produce modest increases in glutathione levels, such as: Incorporating more sulfur-rich foods into your diet (meat, garlic, onion, kale, broccoli, etc.) Adding more dairy to the diet Boosting protein intake Exercising regularly However, to maximally increase glutathione levels to complement endogenous glutathione production and get the most from the master antioxidant, TRT Miami patients can boost their levels through highly effective, cost-effective glutathione injections

Chronobiol Int 20: 921962

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