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Name: can l carnitine cause constipation The Role of L-Carnitine in Kidney Disease and Related Metabolic Dysfunctions How to Take L-Carnitine to
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Summary Keywords vitamin C, ascorbic acid, cancer prevention, cancer treatment, tumor microenvironment Citation Cao X, Yi Y, Ji M, Liu Y, Wang D and Zhu H (2025) The dual role of vitamin C in cancer: from antioxidant prevention to prooxidant therapeutic applications

It increases MMPs (e.g., MMP-2, MMP-9) activity and inhibits TIMPs (e.g., TIMP-1, TIMP-2) expression [149], promoting ECM degradation and reducing its accumulation

Specifically, activator protein-1 (AP-1) and early growth response (EGR) reprogram Kupffer cell properties and LXR functions required for survival to transform the associated macrophage phenotype and drive myeloid cell diversity in NASH [53]