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The biological function of the observed hypermalonylation in cardiomyopathy is still unclear

L.WongW

GRP78 is a member of the chaperone HSP70 family which is closely relevant to the endothelial dysfunction in the development of AS, with a fundamental role in protecting protein stabilization and also in anti-inflammation (116)

Nevertheless, macrophage cholesterol efflux to HDL reduces inflammation and the atherosclerotic burden, and is the first step in reverse cholesterol transport (RCT) (Figure 10) (685-687)