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Currently, novel AR antagonist-HSP90 inhibitor conjugates can degrade not only the full-length AR protein but also the AR splice variant AR-V7

Figure 3 2.1.1 Impact of dysregulation in gliomas One key regulatory step in the kynurenine pathway is the uptake of tryptophan and kynurenine (KYN) via transporters such as L-type amino acid transporter(LAT1) and ASCT2, which are often overexpressed in glioma

Wang Y-X, Feng W, Zeng Q, Sun Y, Wang P, You L, Yang P, Huang Z, Yu S-L, Lu W-Q (2016) Variability of metal levels in spot, first morning, and 24-Hour urine samples over a 3-Month period in healthy adult Chinese men

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