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Research published in Naunyn-Schmiedeberg Archives of Pharmacology confirmed this in isolated human atrial tissue

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Since all SODs are endogenous enzymes, SOD murine trials are conducted through mimetics like 4-Hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl (tempol), nanoformulated SOD (NanoSOD), and hydrodynamic injections of SOD3 plasmids