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19 In addition, the following risk factors for major depression have been identified: Family history of depression Risk of major depression is three times greater among people who have a first-degree relative with major depression 5 Maltreatment during childhood, including neglect and abuse 20,21 Adverse life events, such as unemployment, financial hardship, divorce, grief and loss, and catastrophic world events such as natural disasters 8 Chronic or severe stress 22 Loneliness 23 Certain personality traits, including shyness and introversion, agreeableness, and neuroticism (moodiness with a tendency to feel emotions such as worry, fear, anger, frustration, envy, guilt, loneliness, and depressed mood) 20 Sleep disorders 24 Other psychiatric disorders, such as substance use disorders, anxiety disorders, and post-traumatic stress disorder (PTSD) 4 5 Physiological Factors that May Contribute to Depression Depression is a complex disorder with numerous contributing and proposed causes

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It helps increase NAD+ levels , supporting cellular repair, metabolism, and overall vitality