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and in neuronal cultures, it supports BDNF signaling and mitochondrial function

[DOI] [PMC free article] [PubMed] [Google Scholar] 61

ATM, ATR, and DNA-PK: the trinity at the heart of the DNA damage response

A recent systematic review and meta-analysis reported positive effects of exogenous melatonin on sleep quality in adults with metabolic disorders, respiratory diseases, and primary sleep disorders, while no statistically significant findings were reported for individuals with mental disorders and neurodegenerative diseases [11]