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Glucose deprivation induces heme oxygenase-1 gene expression by a pathway independent of the unfolded protein response

4-HP can be found naturally in human tissues and biofluids and in several natural foods, and it is also produced by multiple microbial species 25

Inclusion criteria requires patients to be over 18 years old, speak English, and have hepatocellular carcinoma (BCLC C with child class A or BCLC A/B/C with child class B) or child class B or C with one complication