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Metformin suppresses foam cell formation, inflammation and ferroptosis via the AMPK/ERK signaling pathway in oxLDLinduced THP1 monocytes

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Other reasons for hyper-vascularization are UV-induced solar elastosis and elevation of cytokines such as stem cell factor (SCF), inducible nitric oxide synthase (iNOS), and c-KIT (a strong melanogenic cytokine) (Kang et al., 2006