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Senolytic therapies like FOXO4-DRI may offer a promising approach to modulate aging and halt neurodegenerative disease progression (4)

Key Points The drugs that were known to be effective for the treatment of depression during the 1960s and 1970s were inhibitors of monoamine oxidase, which degraded the monoamines, or tricyclic antidepressants, which inhibited the uptake of monoamines

Selenium Nanodots (SENDs) as Antioxidants and Antioxidant-Prodrugs to Rescue Islet Cells in Type 2 Diabetes Mellitus by Restoring Mitophagy and Alleviating Endoplasmic Reticulum Stress