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All participants were examined at baseline, after 2 weeks, and after 16 weeks of supplementation

doi: 10.1038/s41467-020-14787-y 54 DufortC.WangY.HuX

(2011) analyzed differences in the expression levels of MPO-related genes between a stroke group and a control group and found a positive correlation between the rs8178406 sequence in the MPO gene and stroke occurrence, providing the additional evidence that MPO is involved in stroke susceptibility and demonstrating a significant correlation between the MPO gene and stroke occurrence

The mechanism involves the dependence of key family members of AP-1 and NFB on Nrf1 and Nrf2 for their expression (Yang et al., 2005a)