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Glutathione is an important antioxidant in the body

Mapping the immune microenvironment for mandibular alveolar bone homeostasis at single-cell resolution

Results Neuronal GCLC knockout leads to brain atrophy accompanied by neuronal cell death To examine how the declines in GCLC and glutathione might affect brain homeostasis, we prepared GCLC floxed X CaMKII-Cre (GCLC-KO) mice whose GCLC expression is deleted in calcium/calmodulin-dependent protein kinase II (CaMKII)-positive neurons

MITOCHONDRIAL MEMBRANE PERMEABILIZATION AND RELEASE OF PROAPOPTOTIC PROTEINS While mitochondrial proteins are normally secured in the IMS, understanding the mechanism of release may be of relevance to control cell death