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Early agents such as hexamethonium were the first effective antihypertensives, demonstrating that pharmacologic reduction of blood pressure could prevent cardiac complications (left panel)

In addition, GF mice have different glycosylation characteristics[34]

However, the great performance of LDM_res comes at the cost of significantly higher computational requirements for both training and inference when compared to the other DL models, i.e., the U-Net or the GAN