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10.12360/CPB202111091 93 ZhangY

GSH is a main player in liver metabolic pathways that detoxify toxicants and drugs coming from the gut that could harm the liver

Yeung LK, Alschuler DM, Wall M, et al

Similar to MAO-B inhibitors, COMT inhibitors, such as entacapone and tolcapone, can extend the duration of levodopas action in the central nervous system, thereby enhancing therapeutic efficacy